Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17494530 | 0.89 | — | — | |
| SCHEMBL10503016 | 0.82 | — | — | |
| SCHEMBL10501912 | 0.76 | — | — | |
| SCHEMBL7679209 | 0.76 | PRKCI (0.36) | CRHR1 | |
| SCHEMBL9821986 | 0.74 | CRHR1 (0.37) | CRHR1 | |
| SCHEMBL9821919 | 0.74 | CRHR1 (0.37) | CRHR1 | |
| SCHEMBL7930932 | 0.71 | SLC29A1 (0.47) | — | |
| SCHEMBL6227893 | 0.71 | ALDH1A1 (0.33) | CRHR1 | |
| SCHEMBL29152865 | 0.71 | PDE4A (0.35) | CRHR1 | |
| SCHEMBL7940047 | 0.65 | HTT (0.36) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |