Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937714 | 0.85 | HDAC4 (0.35) | RIPK1HDAC4HDAC2HDAC8 | |
| SCHEMBL449071 | 0.83 | RIPK1 (0.35) | RIPK1HDAC4HDAC2HDAC8 | |
| SCHEMBL4074326 | 0.79 | HDAC4 (0.37) | RIPK1HDAC4HDAC2HDAC8 | |
| SCHEMBL7933687 | 0.76 | RIPK1 (0.31) | RIPK1HDAC4HDAC2HDAC8 | |
| SCHEMBL7937726 | 0.76 | MAPK1 (0.48) | RIPK1 | |
| SCHEMBL4664725 | 0.74 | — | — | |
| SCHEMBL16722408 | 0.73 | HDAC4 (0.37) | HDAC4HDAC2HDAC8 | |
| SCHEMBL17710275 | 0.73 | MAPK1 (0.49) | RIPK1 | |
| SCHEMBL30801347 | 0.72 | KDM4E (0.33) | RIPK1 | |
| SCHEMBL20302226 | 0.72 | GBA1 (0.35) | HDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300387-B2 | USED FOR PRODUCTION OF CORES OF AUTOMOBILE INTERIOR MATERIALS, SOUND ABSORBERS OF AIR CONDITIONERS, GLASS MAT, CONSTRUCTIONAL SOUND INSULATORS; STRENGTH AND HEAT RESISTANCE | KAO CORPORATION (JP) | 2001-10-09 | — | — | US | disclosed |
| US-20010020048-A1 | Molding composition | KAO CORPORATION (JP) | 2001-09-06 | — | — | US | disclosed |