Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17710275 | 0.93 | MAPK1 (0.49) | MAPK1ALDH1A1ALOX15RIPK1CHRM2 | |
| SCHEMBL449071 | 0.82 | RIPK1 (0.35) | RIPK1CHRM2CHRM1CHRM3CACNA1F | |
| SCHEMBL16103263 | 0.80 | MAPK1 (0.59) | MAPK1ALDH1A1ALOX15CHRM2CHRM1 | |
| SCHEMBL7937714 | 0.78 | HDAC4 (0.35) | RIPK1 | |
| SCHEMBL4074326 | 0.78 | HDAC4 (0.37) | ALDH1A1ALOX15RIPK1KIF11TACR1 | |
| SCHEMBL28482720 | 0.77 | MAPK1 (0.55) | MAPK1ALDH1A1ALOX15RIPK1CHRM2 | |
| SCHEMBL1077953 | 0.76 | RIPK1 (0.48) | ALDH1A1RIPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL7937716 | 0.76 | RIPK1 (0.35) | RIPK1 | |
| SCHEMBL7933687 | 0.75 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL4360668 | 0.75 | RIPK1 (0.47) | MAPK1ALDH1A1ALOX15RIPK1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300387-B2 | USED FOR PRODUCTION OF CORES OF AUTOMOBILE INTERIOR MATERIALS, SOUND ABSORBERS OF AIR CONDITIONERS, GLASS MAT, CONSTRUCTIONAL SOUND INSULATORS; STRENGTH AND HEAT RESISTANCE | KAO CORPORATION (JP) | 2001-10-09 | — | — | US | disclosed |
| US-20010020048-A1 | Molding composition | KAO CORPORATION (JP) | 2001-09-06 | — | — | US | disclosed |