SCHEMBL7937748

SCHEMBL7937748

[CH2]C(=O)COCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8676200 0.84 CES2 (0.48) CES2
SCHEMBL1718927 0.80
SCHEMBL395577 0.79
SCHEMBL2868177 0.78
SCHEMBL14269210 0.77 ALDH1A1 (0.33)
SCHEMBL1104613 0.76
SCHEMBL9302267 0.75 CES2 (0.32) CES2
SCHEMBL13876101 0.75
SCHEMBL14269224 0.75 THRB (0.30)
SCHEMBL14269215 0.75 TSHR (0.39) CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0702686-B1 ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS KIMBERLY CLARK CO (US) 2001-09-05 EP disclosed
US-5854147-A Non-woven web containing antimicrobial siloxane quaternary ammonium salts KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-12-29 US disclosed
US-5777010-A BLEND WITH THERMOPLASTIC POLYOLEFIN KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-07-07 US disclosed
EP-0760821-A1 ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS KIMBERLY-CLARK CORPORATION (US) 1997-03-12 EP disclosed
US-5569732-A TRISILOXANE KIMBERLY-CLARK CORPORATION (US) 1996-10-29 US disclosed
US-5567372-A Method for preparing a nonwoven web containing antimicrobial siloxane quaternary ammonium salts KIMBERLY-CLARK CORPORATION (US) 1996-10-22 US disclosed
EP-0702686-A1 ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS KIMBERLY-CLARK CORPORATION (US) 1996-03-27 EP disclosed
WO-1995032977-A1 ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS KIMBERLY-CLARK CORPORATION (US) 1995-12-07 WO disclosed
WO-1994029325-A1 ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS KIMBERLY-CLARK CORPORATION (US) 1994-12-22 WO disclosed