Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28153776 | 0.91 | LMNA (0.46) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL28154762 | 0.91 | LMNA (0.46) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL28154741 | 0.91 | LMNA (0.46) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL28271792 | 0.91 | LMNA (0.46) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL377895 | 0.91 | LMNA (0.46) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL28271647 | 0.91 | LMNA (0.46) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL28161676 | 0.91 | LMNA (0.46) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL28154786 | 0.91 | LMNA (0.46) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL28149407 | 0.91 | ALDH1A1 (0.50) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL8835968 | 0.89 | LMNA (0.48) | LMNAALDH1A1TDP1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702686-B1 | ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS | KIMBERLY CLARK CO (US) | 2001-09-05 | — | — | EP | disclosed |
| US-5853641-A | Method for preparing polyolefin fibers containing antimicrobial siloxane quarternary ammonium salts | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-12-29 | — | — | US | disclosed |
| US-5854147-A | Non-woven web containing antimicrobial siloxane quaternary ammonium salts | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-12-29 | — | — | US | disclosed |
| US-5853883-A | Polyolefin fibers containing antimicrobial siloxane quaternary ammonium salts | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-12-29 | — | — | US | disclosed |
| US-5777010-A | BLEND WITH THERMOPLASTIC POLYOLEFIN | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0760821-A1 | ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS | KIMBERLY-CLARK CORPORATION (US) | 1997-03-12 | — | — | EP | disclosed |
| US-5569732-A | TRISILOXANE | KIMBERLY-CLARK CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
| US-5567372-A | Method for preparing a nonwoven web containing antimicrobial siloxane quaternary ammonium salts | KIMBERLY-CLARK CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0702686-A1 | ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS | KIMBERLY-CLARK CORPORATION (US) | 1996-03-27 | — | — | EP | disclosed |
| WO-1995032977-A1 | ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS | KIMBERLY-CLARK CORPORATION (US) | 1995-12-07 | — | — | WO | disclosed |
| WO-1994029325-A1 | ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS | KIMBERLY-CLARK CORPORATION (US) | 1994-12-22 | — | — | WO | disclosed |