Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937770 | 0.89 | LMNA (0.46) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL28149407 | 0.84 | ALDH1A1 (0.50) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL7086461 | 0.83 | ALDH1A1 (0.42) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL506080 | 0.83 | LMNA (0.65) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL22588820 | 0.83 | LMNA (0.65) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL24981778 | 0.83 | LMNA (0.65) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL22588823 | 0.83 | LMNA (0.65) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL21118936 | 0.83 | LMNA (0.65) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL16594216 | 0.83 | LMNA (0.65) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL1760772 | 0.83 | LMNA (0.65) | LMNADNM1ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760821-A1 | ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS | KIMBERLY-CLARK CORPORATION (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032977-A1 | ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS | KIMBERLY-CLARK CORPORATION (US) | 1995-12-07 | — | — | WO | disclosed |