SCHEMBL7937807

SCHEMBL7937807

CC1=Cc2c(C(C)C)cccc2C1[Si](c1ccccc1)(c1ccccc1)C1C(C)=Cc2c(C(C)C)cccc21.[SiH3]c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052105 0.95 TSHR (0.33) ALDH1A1ALOX15TSHR
SCHEMBL7052666 0.82 TSHR (0.32) ALDH1A1ALOX15TSHR
SCHEMBL7053998 0.81 LMNA (0.32) ALDH1A1ALOX15TSHR
SCHEMBL7054857 0.80 LMNA (0.31) ALDH1A1ALOX15TSHR
SCHEMBL7053648 0.80 LMNA (0.34) ALDH1A1ALOX15TSHR
SCHEMBL7037674 0.77 LMNA (0.34) ALDH1A1ALOX15TSHR
SCHEMBL1452753 0.75 ALDH1A1 (0.31) ALDH1A1
SCHEMBL7056002 0.75 LMNA (0.35) TSHR
SCHEMBL7053482 0.75 LMNA (0.35) TSHR
SCHEMBL5837366 0.73 PDCD1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed