Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 5/20 | 0.72 |
| ▸ | FBP1 | P09467 | 14/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 3/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | ABL2 | P42684 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GALR2 | O43603 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491460 | 1.00 | VCP (0.72) | VCPFBP1ALDH1A1MAPTHTT | |
| SCHEMBL30592059 | 1.00 | VCP (0.72) | VCPFBP1ALDH1A1MAPTHTT | |
| SCHEMBL807786 | 0.84 | VCP (0.61) | VCPFBP1ALDH1A1MAPTHTT | |
| SCHEMBL807974 | 0.84 | VCP (0.66) | VCPFBP1ALDH1A1MAPTHTT | |
| SCHEMBL8010045 | 0.84 | EGFR (0.72) | VCPFBP1ALDH1A1MAPTHTT | |
| SCHEMBL793479 | 0.84 | VCP (0.66) | VCPFBP1ALDH1A1MAPTHTT | |
| SCHEMBL793177 | 0.84 | VCP (0.61) | VCPFBP1ALDH1A1MAPTHTT | |
| SCHEMBL15466842 | 0.81 | FBP1 (0.58) | VCPFBP1ALDH1A1MAPTHTT | |
| SCHEMBL15466841 | 0.81 | FBP1 (0.58) | VCPFBP1ALDH1A1MAPTHTT | |
| SCHEMBL1722329 | 0.80 | FBP1 (0.57) | VCPFBP1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025045746-A1 | PYRAZOLE DERIVATIVES AS SARM1 INHIBITORS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-03-06 | — | — | WO | disclosed |
| EP-4086240-B1 | PYRROLIDINONE HERBICIDES | FMC CORP (US) | 2025-02-05 | — | — | EP | disclosed |
| US-12077503-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2024-09-03 | — | — | US | disclosed |
| US-20240208992-A1 | MACROCYCLES AS CFTR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-27 | — | — | US | disclosed |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| EP-4308575-A1 | MACROCYCLES AS CFTR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2024-01-24 | — | — | EP | disclosed |
| CN-116981672-A | Macrocyclic compounds as CFTR modulators | 爱杜西亚药品有限公司 | 2023-10-31 | — | — | CN | disclosed |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230270111-A1 | PYRROLIDINONES HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY | 2023-08-31 | — | — | US | disclosed |
| US-11589583-B2 | Pyrrolidinones herbicides | FMC CORPORATION (US) | 2023-02-28 | — | — | US | disclosed |
| EP-1891019-B1 | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | AVENTIS PHARMA INC (US) | 2012-07-25 | — | — | EP | disclosed |
| US-8193183-B2 | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin D2 receptor antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2012-06-05 | — | — | US | disclosed |
| WO-2012035078-A1 | 17α-HYDROXYLASE/C17,20-LYASE INHIBITORS | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |
| US-7517889-B2 | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin D2 receptor antagonists | AVENTIS PHARMACEUTICALS, INC. (US) | 2009-04-14 | — | — | US | disclosed |
| EP-1891019-A2 | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| US-20070265291-A1 | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070244131-A1 | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070225267-A1 | 3-(2-Acylamino-1-Hydroxyethyl)-Morpholine Derivatives and Their Use as Bace Inhibitors | ELI LILLY AND COMPANY | 2007-09-27 | — | — | US | disclosed |
| CN-101039920-A | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin d2 receptor antagonists | AVENTIS PHARMA INC (US) | 2007-09-19 | — | — | CN | disclosed |
| WO-2006044732-A2 | 2, 6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11589583-B2 | Pyrrolidinones herbicides | DDT, ARG1, CYP1B1 | VCP 4007/4885FBP1 1229/4885ALDH1A1 406/4885 |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | VCP 3583/4885FBP1 3219/4885ALDH1A1 1202/4885 |
| US-20070225267-A1 | 3-(2-Acylamino-1-Hydroxyethyl)-Morpholine Derivatives and Their Use as Bace Inhibitors | BACE1, BACE2, APP | VCP 1344/4885FBP1 2487/4885ALDH1A1 893/4885 |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | VCP 3582/4885FBP1 3184/4885ALDH1A1 1182/4885 |
| US-20230270111-A1 | PYRROLIDINONES HERBICIDES | DDT, ARG1, CYP1B1 | VCP 4007/4885FBP1 1229/4885ALDH1A1 406/4885 |
| US-12077503-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | VCP 3582/4885FBP1 3184/4885ALDH1A1 1182/4885 |
| US-20240208992-A1 | MACROCYCLES AS CFTR MODULATORS | CFTR, PKD1, ARRB1 | VCP 1591/4885FBP1 1930/4885ALDH1A1 2257/4885 |
| US-20070244131-A1 | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | CYSLTR2, PTGER2, CYSLTR1 | VCP 3591/4885FBP1 1222/4885ALDH1A1 639/4885 |
| US-20070265291-A1 | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | CYSLTR2, PTGER2, CYSLTR1 | VCP 3591/4885FBP1 1222/4885ALDH1A1 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.