Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16715306 | 0.83 | CXCL8 (0.37) | CNR2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL807758 | 0.81 | CNR2 (0.41) | CNR2ACP3POLBMAPK1HSD11B1 | |
| SCHEMBL16715303 | 0.80 | CYP3A4 (0.43) | CNR2ACP3POLBMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15226476 | 0.80 | CNR2 (0.40) | CNR2ACP3POLBMAPK1HSD11B1 | |
| SCHEMBL793190 | 0.79 | MEN1 (0.39) | POLBMAPK1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL15226732 | 0.78 | CNR2 (0.42) | CNR2ACP3POLBMAPK1HSD11B1 | |
| SCHEMBL16715287 | 0.77 | HPGD (0.40) | CNR2MAPK1ALDH1A1TSHRLMNA | |
| SCHEMBL794263 | 0.77 | ALDH1A1 (0.41) | ACP3POLBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL167206 | 0.74 | CNR2 (0.42) | CNR2ACP3POLBMAPK1HSD11B1 | |
| SCHEMBL807931 | 0.72 | POLB (0.46) | CNR2POLBMAPK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616448-B1 | SUBSTITUTED PHENYLACETATE AND PHENYLPROPANE AMIDES AND USE THEREOF | BAYER IP GMBH (DE) | 2016-07-20 | — | — | EP | disclosed |
| US-9034855-B2 | Substituted phenylacetate and phenylpropane amides and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| EP-2616448-A1 | SUBSTITUTED PHENYLACETATE AND PHENYLPROPANE AMIDES AND USE THEREOF | Bayer Intellectual Property GmbH (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035075-A1 | SUBSTITUTED PHENYLACETATE AND PHENYLPROPANE AMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-22 | — | — | WO | disclosed |