Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.38 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.37 |
| ▸ | MICA | Q29983 | 2/20 | 0.37 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794179 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL793329 | 0.83 | TACR1 (0.41) | ALDH1A1MEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL794506 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL807649 | 0.81 | CES2 (0.44) | ALDH1A1MEN1CYP1A2POLBCYP3A4 | |
| Hydrochloric Acid SCHEMBL15226688 | 0.80 | EPHX1 (0.44) | ALDH1A1MEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL15226545 | 0.79 | TACR1 (0.43) | ALDH1A1MEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL16715277 | 0.78 | PPARG (0.40) | ALDH1A1MEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL793786 | 0.77 | CNR2 (0.38) | ALDH1A1MEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL16674214 | 0.75 | PNMT (0.52) | ALDH1A1MEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL10129819 | 0.74 | CTSS (0.46) | ALDH1A1MEN1CYP1A2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616448-B1 | SUBSTITUTED PHENYLACETATE AND PHENYLPROPANE AMIDES AND USE THEREOF | BAYER IP GMBH (DE) | 2016-07-20 | — | — | EP | disclosed |
| US-9034855-B2 | Substituted phenylacetate and phenylpropane amides and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| EP-2616448-A1 | SUBSTITUTED PHENYLACETATE AND PHENYLPROPANE AMIDES AND USE THEREOF | Bayer Intellectual Property GmbH (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035075-A1 | SUBSTITUTED PHENYLACETATE AND PHENYLPROPANE AMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-22 | — | — | WO | disclosed |