Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | ESRRG | P62508 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bisphenol A SCHEMBL4907613 | 0.92 | ALDH1A1 (0.58) | ESR1ESR2CYP3A4HSD17B10AR | |
| SCHEMBL6671840 | 0.90 | HSD17B10 (0.56) | HSD17B10ALDH1A1HSD11B1GPR35ACHE | |
| SCHEMBL27496976 | 0.89 | LMNA (0.61) | ESR1ESR2CYP3A4HSD17B10AR | |
| SCHEMBL836917 | 0.89 | ESR1 (0.53) | ESR1ESR2CYP3A4HSD17B10AR | |
| P-Nitrophenol SCHEMBL28178085 | 0.89 | LMNA (0.61) | ESR1ESR2CYP3A4HSD17B10AR | |
| SCHEMBL28198294 | 0.85 | HSD11B1 (0.45) | ESR1ESR2CYP3A4HSD17B10AR | |
| P-Nitrophenol SCHEMBL1115712 | 0.83 | HSD17B10 (0.58) | HSD17B10TSHRALDH1A1ACHEMEN1 | |
| P-Nitrophenol SCHEMBL11048842 | 0.83 | CES1 (0.58) | HSD17B10HPGDTSHRALDH1A1GPR35 | |
| P-Nitrophenol SCHEMBL29806213 | 0.83 | CES1 (0.58) | HSD17B10HPGDTSHRALDH1A1GPR35 | |
| P-Nitrophenol SCHEMBL1839 | 0.83 | CES1 (0.58) | HSD17B10HPGDTSHRALDH1A1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| CN-1272884-A | Adipocyte-specific protein homologs | ZYMOGENETICS INC (US) | 2000-11-08 | — | — | CN | disclosed |
| CN-1263882-A | Method for preparing fluorine-substituted aromatic compound | MITSUI CHEMICALS INC (JP) | 2000-08-23 | — | — | CN | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |