Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793816 | 0.81 | PI4KB (0.43) | PI4KBDGAT1PDE4APDE4BPDE4C | |
| SCHEMBL1694727 | 0.75 | PI4KB (0.48) | PI4KBDGAT1PDE4APDE4BPDE4C | |
| SCHEMBL653518 | 0.74 | PI4KB (0.57) | PI4KBDGAT1KIT | |
| SCHEMBL654042 | 0.68 | PI4KB (0.56) | PI4KBKIT | |
| SCHEMBL655731 | 0.68 | PI4KB (0.59) | PI4KBKIT | |
| SCHEMBL653903 | 0.67 | HSP90AA1 (0.51) | KIT | |
| SCHEMBL654247 | 0.65 | HRH4 (0.48) | KIT | |
| SCHEMBL655119 | 0.65 | PI4KB (0.59) | PI4KB | |
| SCHEMBL654776 | 0.64 | ALDH1A1 (0.51) | KIT | |
| SCHEMBL652590 | 0.64 | HRH4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405973-A2 | THIAZOLOPYRIMIDINE MODULATORS AS IMMUNOSUPPRESSIVE AGENTS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-01-18 | — | — | EP | disclosed |