Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367374 | 0.82 | CA1 (0.38) | TDP1ALDH1A1 | |
| SCHEMBL10202574 | 0.81 | L3MBTL1 (0.42) | L3MBTL1TDP1NFE2L2ALDH1A1HTR1A | |
| SCHEMBL29635691 | 0.78 | EPHX2 (0.43) | L3MBTL1TDP1NFE2L2ALDH1A1SLC6A2 | |
| SCHEMBL255271 | 0.78 | EPHX2 (0.43) | L3MBTL1TDP1NFE2L2ALDH1A1SLC6A2 | |
| SCHEMBL26622140 | 0.77 | PARP10 (0.34) | L3MBTL1TDP1NFE2L2ALDH1A1HTR1A | |
| SCHEMBL9678359 | 0.76 | L3MBTL1 (0.38) | L3MBTL1TDP1NFE2L2ALDH1A1HTR1A | |
| SCHEMBL17481524 | 0.74 | L3MBTL1 (0.41) | L3MBTL1TDP1NFE2L2ALDH1A1HTR1A | |
| SCHEMBL19387683 | 0.74 | L3MBTL1 (0.46) | L3MBTL1TDP1NFE2L2ALDH1A1ESR1 | |
| SCHEMBL10917461 | 0.73 | TSHR (0.36) | TDP1MAPK1 | |
| SCHEMBL914798 | 0.73 | LMNA (0.43) | L3MBTL1TDP1ALDH1A1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |
| US-4876376-A | Process for the halogenation, nitration and fluorination of aromatic derivatives | RHONE-POULENC SPECIALISTES CHIMIQUES (FR) | 1989-10-24 | — | — | US | disclosed |
| EP-0130876-B1 | PROCESS FOR THE SIMULTANEOUS HALOGENATION AND FLUORINATION OF AROMATIC COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1988-04-20 | — | — | EP | disclosed |
| EP-0130875-B1 | PROCESS FOR THE HALOGENATION-NITRATION FLUORINATION OF AROMATIC COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1987-07-22 | — | — | EP | disclosed |
| US-4575571-A | HALOGEN IN LIQUID HYDROGEN FLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1986-03-11 | — | — | US | disclosed |
| EP-0113625-B1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYLATED BENZENIC COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1985-07-10 | — | — | EP | disclosed |
| EP-0130875-A1 | Process for the halogenation-nitration fluorination of aromatic compounds | RHONE-POULENC CHIMIE (FR) | 1985-01-09 | — | — | EP | disclosed |
| EP-0130876-A1 | Process for the simultaneous halogenation and fluorination of aromatic compounds | RHONE-POULENC CHIMIE (FR) | 1985-01-09 | — | — | EP | disclosed |
| EP-0113625-A1 | Process for the preparation of trifluoromethylated benzenic compounds | RHONE-POULENC CHIMIE (FR) | 1984-07-18 | — | — | EP | disclosed |