Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991056 | 0.87 | CA1 (0.62) | CA1CA2CA7CA9CA12 | |
| SCHEMBL10917461 | 0.84 | TSHR (0.36) | CA1CA2CA7CA9CA12 | |
| SCHEMBL28003345 | 0.84 | LMNA (0.43) | TSHRALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL914798 | 0.84 | LMNA (0.43) | TSHRALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL9215888 | 0.83 | KDM4E (0.35) | LMNA | |
| SCHEMBL10913428 | 0.83 | DRD1 (0.40) | TDP1LMNA | |
| SCHEMBL7192709 | 0.82 | TSHR (0.43) | CA1CA2CA7CA9CA12 | |
| SCHEMBL6298496 | 0.82 | CA2 (0.50) | CA1CA2CA12CA4CA14 | |
| SCHEMBL7938418 | 0.82 | L3MBTL1 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL10910618 | 0.82 | DRD1 (0.39) | ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365915-B1 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| US-4956370-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| EP-0368008-A1 | Fluorine-containing phenols | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |
| EP-0365915-A2 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |