Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815463 | 0.90 | MEN1 (0.47) | ALDH1A1GAAMEN1KMT2ALMNA | |
| SCHEMBL6815612 | 0.86 | HDAC1 (0.36) | RAB9ANPC1KDM4ENPSR1ALDH1A1 | |
| SCHEMBL7945481 | 0.84 | RAB9A (0.56) | RAB9ANPC1KDM4EALDH1A1GAA | |
| SCHEMBL6819653 | 0.84 | KDM4E (0.48) | RAB9ANPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL6819236 | 0.83 | IRAK4 (0.39) | RAB9ANPC1KDM4ENPSR1ALDH1A1 | |
| SCHEMBL6811016 | 0.82 | CA1 (0.42) | RAB9ANPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL7945512 | 0.81 | NPC1 (0.43) | RAB9ANPC1KDM4ERXFP1NPSR1 | |
| SCHEMBL6811496 | 0.81 | TSHR (0.49) | RAB9ANPC1ALDH1A1GAAMEN1 | |
| SCHEMBL6815630 | 0.80 | BCAT2 (0.41) | RAB9ANPC1NPSR1ALDH1A1MEN1 | |
| SCHEMBL6811424 | 0.79 | MEN1 (0.49) | RAB9ANPC1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |