Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816133 | 0.81 | GCGR (0.40) | NPC1RAB9AKDM4ENPSR1MEN1 | |
| SCHEMBL7938420 | 0.81 | RAB9A (0.45) | NPC1RAB9ARXFP1KDM4EHPGD | |
| SCHEMBL6819842 | 0.79 | BCAT2 (0.52) | NPC1RAB9AKDM4ENPSR1MEN1 | |
| SCHEMBL6816285 | 0.74 | KDR (0.51) | NPSR1MEN1KMT2AGAAMAPT | |
| SCHEMBL7971251 | 0.72 | ROCK2 (0.36) | NPC1RAB9ARXFP1KDM4ENPSR1 | |
| SCHEMBL11148177 | 0.71 | ALDH1A1 (0.63) | NPC1RAB9ARXFP1KDM4ENPSR1 | |
| SCHEMBL4351338 | 0.71 | ALOX15 (0.59) | KDM4EHPGDUSP2NPSR1MEN1 | |
| SCHEMBL6815463 | 0.71 | MEN1 (0.47) | MEN1KMT2AGAAMAPTPOLB | |
| SCHEMBL6816263 | 0.71 | GCGR (0.43) | MAPTLMNA | |
| SCHEMBL4354016 | 0.70 | EGFR (0.48) | NPSR1HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |