SCHEMBL7938428

SCHEMBL7938428

O=C(c1ccccc1)c1ccc(Sc2ccc(O)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.68
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
MAPT P10636 2/20 0.68
RAB9A P51151 2/20 0.68
HPGD P15428 3/20 0.60
ESR1 P03372 1/20 0.60
ESR2 Q92731 1/20 0.60
PKM P14618 1/20 0.60
HTT P42858 1/20 0.60
SRD5A2 P31213 2/20 0.57
CES2 O00748 1/20 0.57
ALDH1A1 P00352 2/20 0.56
NR1H2 P55055 1/20 0.56
NPC1 O15118 1/20 0.55
MAPK1 P28482 1/20 0.50
LIG1 P18858 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
ATM Q13315 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14600281 0.96 LMNA (0.62) LMNAMEN1KMT2AMAPTRAB9A
SCHEMBL9134344 0.92 LMNA (0.71) LMNAMEN1KMT2AMAPTRAB9A
SCHEMBL6787662 0.92 ALDH1A1 (0.67) LMNAMEN1KMT2AMAPTRAB9A
SCHEMBL17828242 0.92 ALDH1A1 (0.67) LMNAMEN1KMT2AMAPTRAB9A
SCHEMBL17828245 0.92 ALDH1A1 (0.67) LMNAMEN1KMT2AMAPTRAB9A
SCHEMBL4563922 0.92 LMNA (0.71) LMNAMEN1KMT2AMAPTRAB9A
SCHEMBL8735147 0.90 LMNA (0.56) LMNAMEN1KMT2AMAPTRAB9A
SCHEMBL21506865 0.90 ALDH1A1 (0.67) LMNAMEN1KMT2AMAPTRAB9A
SCHEMBL385623 0.90 ALDH1A1 (0.67) LMNAMEN1KMT2AMAPTRAB9A
SCHEMBL3282737 0.87 HPGD (0.69) LMNAMEN1KMT2AMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015031927-A1 PHOTOINITIATOR DURST PHOTOTECHNIK DIGITAL TECHNOLOGY GMBH (AT) 2015-03-12 WO disclosed
EP-2302007-B1 Ink composition and inkjet recording method FUJIFILM CORP (JP) 2014-01-29 EP disclosed
US-8342674-B2 Ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2013-01-01 US disclosed
US-8342674-B2 Ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2013-01-01 US disclosed
US-20110074897-A1 INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110074897-A1 INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
EP-2302007-A1 Ink composition and inkjet recording method FUJIFILM Corporation (JP) 2011-03-30 EP disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed