Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | LIG1 | P18858 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128326 | 0.92 | ALDH1A1 (0.55) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL7938428 | 0.90 | LMNA (0.68) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL14600281 | 0.86 | LMNA (0.62) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL1790331 | 0.86 | ALDH1A1 (0.53) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL1127927 | 0.86 | ALDH1A1 (0.49) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL1790602 | 0.86 | ALDH1A1 (0.49) | LMNAMAPTHPGDALDH1A1SRD5A2 | |
| SCHEMBL21679527 | 0.84 | LMNA (0.49) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL13134769 | 0.84 | ALDH1A1 (0.56) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL8736852 | 0.84 | MEN1 (0.43) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL8735142 | 0.84 | RAB9A (0.43) | LMNAMEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120130117-A1 | AROMATIC SULFONIUM SALT COMPOUND | ADEKA CORPORATION (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130117-A1 | AROMATIC SULFONIUM SALT COMPOUND | SLC6A19, ARSA, PAH | LMNA 4190/4885MEN1 3308/4885KMT2A 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.