Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | ESR1 | P03372 | 2/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | LIG1 | P18858 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094666 | 0.92 | ALDH1A1 (0.67) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL4004691 | 0.90 | LMNA (0.67) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL1247035 | 0.87 | PLA2G10 (0.69) | LMNAKMT2ASRD5A2ALDH1A1PLA2G10 | |
| SCHEMBL9400453 | 0.87 | MEN1 (0.86) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL7938553 | 0.87 | MEN1 (0.86) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL124916 | 0.87 | MEN1 (0.86) | LMNAMEN1KMT2AMAPTRAB9A | |
| Benzophenone SCHEMBL27537831 | 0.87 | MEN1 (0.86) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL11130008 | 0.85 | MEN1 (0.83) | LMNAMEN1KMT2AMAPTRAB9A | |
| Potassium SCHEMBL38662363 | 0.85 | MEN1 (0.83) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL7854225 | 0.85 | MEN1 (0.83) | LMNAMEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |