Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.42 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941010 | 0.83 | TDP1 (0.53) | KMT2ATDP1LMNAMAOBPKM | |
| SCHEMBL18833437 | 0.82 | KMT2A (0.69) | KMT2ATDP1SMN1; SMN2LMNAMAOB | |
| SCHEMBL15071685 | 0.77 | ALDH1A1 (0.57) | KMT2ATDP1LMNAMAOBPKM | |
| SCHEMBL6681662 | 0.76 | TDP1 (0.54) | KMT2ATDP1LMNAMAOBPKM | |
| SCHEMBL7056985 | 0.76 | LMNA (0.69) | KMT2ATDP1SMN1; SMN2LMNAMAOB | |
| SCHEMBL23914948 | 0.76 | KMT2A (0.60) | KMT2ATDP1LMNAALDH1A1KDM4E | |
| SCHEMBL27691191 | 0.76 | CYP3A4 (0.54) | KMT2ATDP1SMN1; SMN2LMNAPKM | |
| SCHEMBL15956289 | 0.75 | LMNA (0.70) | LMNAALDH1A1 | |
| SCHEMBL7938747 | 0.74 | TDP1 (0.52) | KMT2ATDP1LMNAMAOBPKM | |
| SCHEMBL5101006 | 0.74 | NR4A2 (0.59) | TDP1LMNAMAOBPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161336-C | Quinoline carboxamides as antiviral agents | �������Ŷ���Լ��������˾ | 2004-08-11 | — | — | CN | disclosed |
| CN-1333753-A | Quinoline carboxamides as antiviral agents | UPJOHN CO (US) | 2002-01-30 | — | — | CN | disclosed |
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |