Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.47 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.47 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15071685 | 0.83 | ALDH1A1 (0.57) | TDP1MAOBTSHRPKMLMNA | |
| SCHEMBL7938481 | 0.83 | KMT2A (0.48) | TDP1MAOBTSHRPKMLMNA | |
| SCHEMBL6681662 | 0.82 | TDP1 (0.54) | TDP1MAOBTSHRPKMLMNA | |
| SCHEMBL7056985 | 0.82 | LMNA (0.69) | TDP1MAOBTSHRLMNAKDM4E | |
| SCHEMBL4156926 | 0.82 | LMNA (0.53) | TDP1TSHRLMNAKDM4EALDH1A1 | |
| SCHEMBL7519027 | 0.81 | LMNA (0.58) | LMNAKDM4EALDH1A1TP53 | |
| SCHEMBL28254045 | 0.81 | LMNA (0.58) | TDP1MAOBPKMLMNAKDM4E | |
| SCHEMBL15956289 | 0.81 | LMNA (0.70) | LMNAALDH1A1TP53P2RX3 | |
| SCHEMBL10343096 | 0.80 | ALDH1A1 (0.57) | MAOBLMNAALDH1A1 | |
| SCHEMBL7938747 | 0.80 | TDP1 (0.52) | TDP1MAOBTSHRPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |