SCHEMBL7938516

SCHEMBL7938516

C=C(CC(=O)OC(C(F)(F)F)C(F)(F)F)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.36
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
GRM1 Q13255 1/20 0.31
GRM2 Q14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL942348 0.85
SCHEMBL7937646 0.81 ALDH1A1 (0.34) TET2
SCHEMBL14338617 0.81 ABHD6 (0.33)
SCHEMBL22615652 0.81 TET2 (0.38) TET2ALOX15HSD17B10TET3TET1
SCHEMBL22841020 0.78 ABHD6 (0.31)
SCHEMBL10988434 0.74 MGAM (0.46)
SCHEMBL7083288 0.74 TSHR (0.41) TET2ALOX15HSD17B10TET3TET1
SCHEMBL2368410 0.73 ALOX15 (0.35) ALOX15HSD17B10
SCHEMBL8830485 0.72 MAPT (0.40) TET2ALOX15HSD17B10TET3TET1
SCHEMBL14556958 0.72 TET2 (0.38) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6312706-B1 ACRYLIC POLYMERS, COPOLYMERS AND POLYSILOXANE URETHANES BAUSCH & LOMB INCORPORATED 2001-11-06 US disclosed