Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519866 | 0.92 | SOS1 (0.70) | HTTSMN1; SMN2SOS1FFAR1FFAR4 | |
| SCHEMBL14138146 | 0.92 | SOS1 (0.70) | HTTSMN1; SMN2SOS1FFAR1FFAR4 | |
| SCHEMBL9779005 | 0.92 | SOS1 (0.70) | HTTSMN1; SMN2SOS1FFAR1FFAR4 | |
| SCHEMBL6848913 | 0.90 | HTT (0.74) | HTTSMN1; SMN2SOS1HTR6PGR | |
| SCHEMBL9323430 | 0.88 | HTT (0.78) | HTTSMN1; SMN2SOS1FFAR1HTR6 | |
| SCHEMBL7937274 | 0.88 | HTR6 (0.70) | HTTSMN1; SMN2HTR6HTR2AHTR2C | |
| SCHEMBL11980110 | 0.88 | HTR6 (0.70) | HTTSMN1; SMN2HTR6HTR2AHTR2C | |
| SCHEMBL778229 | 0.88 | HTR6 (0.70) | HTTSMN1; SMN2HTR6HTR2AHTR2C | |
| SCHEMBL6123058 | 0.86 | HTT (0.81) | HTTSMN1; SMN2SOS1FFAR1HTR6 | |
| SCHEMBL17559302 | 0.86 | HTT (0.81) | HTTSMN1; SMN2SOS1FFAR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |