SCHEMBL778229

SCHEMBL778229

O=S(=O)(c1ccccc1)c1ccc(F)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.70
PKM P14618 1/20 0.59
HTR2A P28223 3/20 0.57
HTR2C P28335 2/20 0.54
KCNH2 Q12809 1/20 0.54
MEN1 O00255 1/20 0.50
MITF O75030 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.50
CASP6 P55212 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA13 Q8N1Q1 1/20 0.50
MMP1 P03956 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11980110 1.00 HTR6 (0.70) HTR6PKMHTR2AHTR2CKCNH2
SCHEMBL7937274 1.00 HTR6 (0.70) HTR6PKMHTR2AHTR2CKCNH2
SCHEMBL7938152 0.93 HTR6 (0.61) HTR6PKMHTR2AHTR2CKCNH2
SCHEMBL2121770 0.89 HSD11B1 (0.55) HTR6PKMHTR2AHTR2CKCNH2
SCHEMBL4328574 0.89 HSD11B1 (0.55) HTR6PKMHTR2AHTR2CKCNH2
SCHEMBL79787 0.89 HSD11B1 (0.55) HTR6PKMHTR2AHTR2CKCNH2
SCHEMBL30072318 0.89 HSD11B1 (0.55) HTR6PKMHTR2AHTR2CKCNH2
SCHEMBL7929318 0.89 MMP1 (0.57) HTR6PKMHTR2AMEN1MITF
SCHEMBL7938520 0.88 HTT (0.62) HTR6PKMHTR2AHTR2CKCNH2
SCHEMBL7938372 0.88 HTR2A (0.58) HTR6PKMHTR2AHTR2CKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4491657-A1 AROMATIC POLYETHER, METHOD FOR PRODUCING AROMATIC POLYETHER, COMPOSITION, AND SHEET Idemitsu Kosan Co.,Ltd. (JP) 2025-01-15 EP claimed
CN-118652422-A High-purity high-temperature-resistant anti-aging low-dielectric polyphenyl ether and preparation method thereof 四川大学 2024-09-17 CN claimed
CN-115926168-B Polyarylethersulfone resin and preparation method thereof 吉林大学 2024-02-23 CN claimed
CN-117551271-A Polymer and preparation method and application thereof 中国科学院福建物质结构研究所 2024-02-13 CN claimed
WO-2023171407-A1 AROMATIC POLYETHER, METHOD FOR PRODUCING AROMATIC POLYETHER, COMPOSITION, AND SHEET 出光興産株式会社 2023-09-14 WO claimed
CN-116284750-A Preparation method of high molecular weight semi-crystalline polyaryletherketone 吉林大学 2023-06-23 CN claimed
CN-110396195-B Polyarylsulfone polymer containing reduced phenazine structure and preparation method thereof 吉林大学 2021-11-16 CN claimed
CN-107474252-B Polyether sulfone containing benzotriazol group and preparation method and application thereof 西南科技大学 2021-03-26 CN claimed
US-9650330-B2 Process for the synthesis of aryl sulfones COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2017-05-16 US claimed
US-20160304447-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-10-20 US claimed
WO-2015087352-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2015-06-18 WO claimed
CN-101704950-B PASSI terpolymer and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2013-07-31 CN claimed
EP-2233512-B1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF NINGBO INST MATERIALS TECHNOLOGY & ENG CAS (CN) 2013-03-20 EP claimed
CN-102030903-B Preparation method of polythioether ketone imide terpolymer NINGBO INST MAT TECH & ENG CAS 2013-03-06 CN claimed
CN-102030903-A Polythioether ketone imide terpolymer and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2011-04-27 CN claimed
US-20110065891-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF CHANGCHUN HIPOLYKING CO.,LTD. (CN) 2011-03-17 US claimed
EP-2233512-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF Ningbo Institute Of Materials Technology And Engineering, Chinese Academy Of Sciences (CN) 2010-09-29 EP claimed
CN-101704950-A PASSI terpolymer and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2010-05-12 CN claimed
CN-101531758-A Polythioetherimide and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2009-09-16 CN claimed
US-6165677-A Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-12-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304447-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES ARSA, TPST2, STS HTR6 1035/4885PKM 2141/4885HTR2A 1044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.