Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11980110 | 1.00 | HTR6 (0.70) | HTR6PKMHTR2AHTR2CKCNH2 | |
| SCHEMBL778229 | 1.00 | HTR6 (0.70) | HTR6PKMHTR2AHTR2CKCNH2 | |
| SCHEMBL7938152 | 0.93 | HTR6 (0.61) | HTR6PKMHTR2AHTR2CKCNH2 | |
| SCHEMBL2121770 | 0.89 | HSD11B1 (0.55) | HTR6PKMHTR2AHTR2CKCNH2 | |
| SCHEMBL4328574 | 0.89 | HSD11B1 (0.55) | HTR6PKMHTR2AHTR2CKCNH2 | |
| SCHEMBL79787 | 0.89 | HSD11B1 (0.55) | HTR6PKMHTR2AHTR2CKCNH2 | |
| SCHEMBL30072318 | 0.89 | HSD11B1 (0.55) | HTR6PKMHTR2AHTR2CKCNH2 | |
| SCHEMBL7929318 | 0.89 | MMP1 (0.57) | HTR6PKMHTR2AMEN1MITF | |
| SCHEMBL7938520 | 0.88 | HTT (0.62) | HTR6PKMHTR2AHTR2CKCNH2 | |
| SCHEMBL7938372 | 0.88 | HTR2A (0.58) | HTR6PKMHTR2AHTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |