Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7775632 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL497000 | 0.77 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL277229 | 0.75 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL1046091 | 0.73 | ALDH1A1 (0.37) | ALDH1A1 | |
| Iodide SCHEMBL27688320 | 0.73 | ALDH1A1 (0.37) | ALDH1A1 | |
| Water SCHEMBL4693457 | 0.73 | ALDH1A1 (0.37) | ALDH1A1 | |
| Bromide SCHEMBL798684 | 0.73 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL4617310 | 0.71 | ALDH1A1 (0.35) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11825950 | 0.71 | TSHR (0.30) | — | |
| SCHEMBL7048307 | 0.68 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |