Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277229 | 0.98 | ALDH1A1 (0.38) | ALDH1A1 | |
| Iodide SCHEMBL27688320 | 0.95 | ALDH1A1 (0.37) | ALDH1A1 | |
| Water SCHEMBL4693457 | 0.95 | ALDH1A1 (0.37) | ALDH1A1 | |
| Bromide SCHEMBL798684 | 0.95 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL7048307 | 0.85 | ALDH1A1 (0.33) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7938586 | 0.77 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL1046091 | 0.76 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL4617310 | 0.74 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL1140010 | 0.69 | GAA (0.34) | ALDH1A1 | |
| SCHEMBL1140038 | 0.69 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660560-B1 | PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2016-03-23 | — | — | EP | claimed |
| EP-2029516-B1 | PROCESS FOR PREPARING FLUORINATED MOLECULES | BAYER IP GMBH (DE) | 2015-08-05 | — | — | EP | claimed |
| EP-2519561-B1 | CHLORO-SUBSTITUTED POLYETHERIMIDES HAVING IMPROVED RELATIVE THERMAL INDEX | SABIC INNOVATIVE PLASTICS IP (NL) | 2014-01-22 | — | — | EP | claimed |
| US-20130303698-A1 | CHLORO-SUBSTITUTED POLYETHERIMIDES HAVING IMPROVED RELATIVE THERMAL INDEX | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-11-14 | — | — | US | claimed |
| US-8524854-B2 | Chloro-substituted polyetherimides having improved relative thermal index | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-09-03 | — | — | US | claimed |
| EP-2519561-A1 | CHLORO-SUBSTITUTED POLYETHERIMIDES HAVING IMPROVED RELATIVE THERMAL INDEX | SABIC Innovative Plastics IP B.V. (NL) | 2012-11-07 | — | — | EP | claimed |
| US-20110263791-A1 | CHLORO-SUBSTITUTED POLYETHERIMIDES HAVING IMPROVED RELATIVE THERMAL INDEX | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-10-27 | — | — | US | claimed |
| WO-2011082147-A1 | CHLORO-SUBSTITUTED POLYETHERIMIDES HAVING IMPROVED RELATIVE THERMAL INDEX | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-07-07 | — | — | WO | claimed |
| EP-1426358-B1 | Slurry preparation of bis(halophthalimides) and of polyether polymers | SABIC INNOVATIVE PLASTICS IP (NL) | 2010-01-27 | — | — | EP | claimed |
| US-20070287855-A1 | Process for Preparing Fluorinated Molecules | BAYER CROPSCIENCE AG (DE) | 2007-12-13 | — | — | US | claimed |
| WO-2001021685-A1 | METHOD FOR PURIFICATION OF AROMATIC POLYETHERS | GENERAL ELECTRIC COMPANY (US) | 2001-03-29 | — | — | WO | claimed |
| US-6191299-B1 | CONTINUOUS PROCESS OF PRODUCING AN AROMATIC CARBONATE BY REACTING AN AROMATIC HYDROXY COMPOUND, CARBON MONOXIDE AND OXYGEN IN THE PRESENCE OF A CATALYST SYSTEM COMPRISING A PALLADIUM SOURCE, A LEAD COMPOUND, AND A HALIDE SOURCE | GENERAL ELECTRIC COMPANY | 2001-02-20 | — | — | US | claimed |
| WO-2000040541-A1 | METHOD FOR MAKING AROMATIC CARBONATES | GENERAL ELECTRIC COMPANY (US) | 2000-07-13 | — | — | WO | claimed |
| WO-2000037417-A1 | METHOD FOR THE PREPARATION OF CARBONATES BY A CONTINUOUS PROCESS | GENERAL ELECTRIC COMPANY (US) | 2000-06-29 | — | — | WO | claimed |
| US-6034262-A | Method for the preparation of carbonates by a continuous process | GENERAL ELECTRIC COMPANY (US) | 2000-03-07 | — | — | US | claimed |
| US-5908952-A | HEXAALKYLGUANIDINIUM CHLORIDE OR BROMIDE AND A GROUP VIIIB METAL SALT OF AT LEAST ONE ALIPHATIC BETA-DIKETONE. | GENERAL ELECTRIC COMPANY (US) | 1999-06-01 | — | — | US | claimed |
| EP-0546930-B1 | Process for obtaining aryle esters by o-dealkylation and applications | POUDRES & EXPLOSIFS STE NALE (FR) | 1996-02-14 | — | — | EP | claimed |
| US-5283358-A | Using an aromatic ether and acyl halide; in presence of hexaalkylguanidinium or tetraalkylphosphonium salt catalyst | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1994-02-01 | — | — | US | claimed |
| EP-0268507-B1 | PROCESS FOR THE PREPARATION OF ALKYLTHIOCHLOROFORMIATES | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1991-03-06 | — | — | EP | claimed |
| US-4820856-A | Process for the production of alkyl thiochloroformates | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1989-04-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287855-A1 | Process for Preparing Fluorinated Molecules | HDHD5, CYP8B1, DHCR7 | ALDH1A1 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.