Benzene

Benzene

SCHEMBL7938846

O=C(O)C1=COCO1.c1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ALDH1A1 P00352 3/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1239684 0.98
SCHEMBL27736614 0.95
Benzene SCHEMBL5373706 0.77 NPC1 (0.42) NPC1RAB9AALDH1A1KMT2AHPGD
SCHEMBL5462773 0.76
SCHEMBL3648506 0.76
SCHEMBL27607282 0.69 ALDH1A1 (0.32) NPC1RAB9AALDH1A1KMT2A
SCHEMBL9055451 0.67 NPC1 (0.41) NPC1RAB9AALDH1A1MAPK1HPGD
SCHEMBL83826 0.64
SCHEMBL4743464 0.64
SCHEMBL8650978 0.62 LMNA (0.35) MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6262090-B1 Aminopyridine-containing thiourea inhibitors of herpes viruses AMERICAN HOME PRODUCTS CORPORATION 2001-07-17 US disclosed