⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763436 | 0.70 | TAS2R8 (0.35) | — | |
| SCHEMBL1239684 | 0.65 | — | — | |
| Benzene SCHEMBL7938846 | 0.64 | NPC1 (0.33) | — | |
| Benzene SCHEMBL5373706 | 0.61 | NPC1 (0.42) | — | |
| SCHEMBL4973085 | 0.61 | — | — | |
| SCHEMBL12815426 | 0.61 | — | — | |
| SCHEMBL14714925 | 0.61 | — | — | |
| SCHEMBL3648506 | 0.60 | — | — | |
| SCHEMBL8650978 | 0.60 | LMNA (0.35) | — | |
| SCHEMBL976981 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4277901-A1 | ISOINDOLINONE COMPOUNDS | Monte Rosa Therapeutics, Inc. (US) | 2023-11-22 | — | — | EP | disclosed |
| EP-4278014-A1 | TREATMENT OF MYC-DRIVEN CANCERS WITH GSPT1 DEGRADERS | Monte Rosa Therapeutics, Inc. (US) | 2023-11-22 | — | — | EP | disclosed |
| WO-2023092175-A1 | NOVEL P2X7 RECEPTOR ANTAGONISTS | THE UNIVERSITY OF SYDNEY (AU) | 2023-06-01 | — | — | WO | disclosed |
| WO-2022152822-A1 | TREATMENT OF MYC-DRIVEN CANCERS WITH GSPT1 DEGRADERS | MONTE ROSA THERAPEUTICS AG (CH) | 2022-07-21 | — | — | WO | disclosed |
| WO-2022152821-A1 | ISOINDOLINONE COMPOUNDS | MONTE ROSA THERAPEUTICS AG (CH) | 2022-07-21 | — | — | WO | disclosed |
| WO-2016038520-A1 | PROCESSES FOR THE PREPARATION OF TICAGRELOR AND ITS INTERMEDIATES | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2016-03-17 | — | — | WO | disclosed |
| EP-2694519-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS MODULATORS OF SPHINGOLIPID SIGNALING AND USES THEREOF | Johann Wolfgang Goethe-Universität (DE) | 2014-02-12 | — | — | EP | disclosed |
| EP-2562171-A1 | GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | National University Corporation Kobe University (JP) | 2013-02-27 | — | — | EP | disclosed |
| WO-2012134629-A1 | QUANTUM DOTS, METHOD, AND DEVICES | QD VISION, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012131096-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS MODULATORS OF SPHINGOLIPID SIGNALING AND USES THEREOF | JOHANN WOLFGANG GOETHE-UNIVERSITÄT, FRANKFURT AM MAIN (DE) | 2012-10-04 | — | — | WO | disclosed |
| WO-2008113851-A2 | NOVEL C11 MODIFIED RETROSTEROIDS AS PROGESTERONE RECEPTOR MODULATOR COMPOUNDS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-09-25 | — | — | WO | disclosed |