Methane

Methane

SCHEMBL7939371

C.CCc1cccc2cc3ccccc3c(O)c12

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.47
GABRB2 P47870 1/20 0.47
CYP1A2 P05177 2/20 0.41
ERBB2 P04626 1/20 0.41
FYN P06241 1/20 0.41
MAOA P21397 1/20 0.41
ACHE P22303 1/20 0.41
AHR P35869 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 2/20 0.40
DNMT1 P26358 1/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
MCL1 Q07820 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
DAO P14920 1/20 0.40
CES1 P23141 1/20 0.39
CASP6 P55212 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11825069 0.81 ALOX5 (0.47) ALDH1A1MCL1KDM4EGLAHPGD
SCHEMBL27586469 0.80 LIPG (0.46) MEN1KMT2AALDH1A1MCL1TDP1
SCHEMBL915442 0.80 ACP3 (0.61) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL915418 0.79 NR1I2 (0.46) GABRA1GABRB2MEN1KMT2AALDH1A1
SCHEMBL7939364 0.79 HTR2A (0.42) GABRA1GABRB2CYP1A2ERBB2FYN
SCHEMBL5751362 0.78 CYP1A2 (0.42) GABRA1GABRB2CYP1A2ERBB2FYN
Propane SCHEMBL243407 0.78 PTPN22 (0.50) CYP1A2MEN1KMT2AALDH1A1CASP6
Methane SCHEMBL2329315 0.77 CYP1A2 (0.50) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL30389687 0.77 GABRA1 (0.56) GABRA1GABRB2ALDH1A1DAOTDP1
SCHEMBL8669787 0.77 GABRA1 (0.56) GABRA1GABRB2ALDH1A1DAOTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242161-B1 ABSORPTION COATINGS USING COPOLYMERS JSR CORPORATION (JP) 2001-06-05 US disclosed