Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.39 |
| ▸ | FEN1 | P39748 | 4/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948269 | 0.89 | DHODH (0.44) | NR1I2CYP2C9DHODHALOX5APFEN1 | |
| SCHEMBL2170747 | 0.85 | S1PR3 (0.40) | NR1I2CYP2C9PDGFRBKDRDHODH | |
| SCHEMBL7945914 | 0.82 | P2RX3 (0.60) | NR1I2CYP2C9ALOX5APFEN1P2RX3 | |
| SCHEMBL1495784 | 0.78 | TDP1 (0.49) | NR1I2CYP2C9P2RX3P2RX2KDM4E | |
| SCHEMBL310982 | 0.78 | ATAD2 (0.51) | NR1I2CYP2C9LMNAP2RX3P2RX2 | |
| SCHEMBL7947936 | 0.76 | CNR2 (0.48) | NR1I2CYP2C9P2RX3P2RX2KDM4E | |
| SCHEMBL7939749 | 0.76 | P2RX3 (0.51) | NR1I2CYP2C9ALOX5APFEN1P2RX3 | |
| SCHEMBL2170986 | 0.74 | NR1I2 (0.45) | NR1I2PDGFRBKDRDHODHHDAC1 | |
| SCHEMBL3057697 | 0.74 | P2RX3 (0.45) | NR1I2CYP2C9P2RX3P2RX2 | |
| SCHEMBL3066007 | 0.74 | KDM4E (0.48) | NR1I2P2RX3P2RX2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033168-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |