Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939408 | 0.89 | CFTR (0.44) | DHODHNR1I2CYP2C9ALOX5APFEN1 | |
| SCHEMBL2171221 | 0.84 | SYK (0.44) | DHODHMAP4K4NR1I2CYP2C9ALOX5AP | |
| SCHEMBL7945914 | 0.83 | P2RX3 (0.60) | NR1I2CYP2C9ALOX5APFEN1P2RX3 | |
| SCHEMBL1495762 | 0.77 | LDHA (0.50) | DHODHMAP4K4LDHAKDM4EALDH1A1 | |
| SCHEMBL7939749 | 0.76 | P2RX3 (0.51) | NR1I2CYP2C9ALOX5APFEN1P2RX3 | |
| SCHEMBL358035 | 0.76 | LDHA (0.58) | DHODHMAP4K4NR1I2LDHAKDM4E | |
| SCHEMBL2188019 | 0.75 | SYK (0.40) | DHODHNR1I2CYP2C9PPARAMRGPRX4 | |
| SCHEMBL16195648 | 0.75 | SCN9A (0.48) | CYP2C9ALOX5APFEN1 | |
| SCHEMBL3066204 | 0.75 | NR1I2 (0.49) | DHODHNR1I2CYP2C9LDHAPPARA | |
| SCHEMBL3476171 | 0.75 | DHODH (0.49) | DHODHNR1I2LDHAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033168-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |