Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13602773 | 0.93 | TSHR (0.47) | CA2IDO1KMT2AMEN1TSHR | |
| SCHEMBL28238110 | 0.87 | LYPLA1 (0.42) | CA2IDO1ESR1ESR2 | |
| SCHEMBL14273420 | 0.86 | TSHR (0.41) | CA2IDO1KMT2AMEN1TSHR | |
| Ethylene Glycol SCHEMBL7940749 | 0.85 | CA2 (0.56) | CA2IDO1ESR1ESR2ABAT | |
| SCHEMBL7940753 | 0.85 | IDO1 (0.54) | CA2IDO1ESR1ESR2ABAT | |
| Hydroquinone SCHEMBL109119 | 0.85 | TSHR (0.59) | CA2IDO1ESR1ESR2KMT2A | |
| Hydroquinone SCHEMBL56540 | 0.85 | TSHR (0.59) | CA2IDO1ESR1ESR2KMT2A | |
| Hydroquinone SCHEMBL1815638 | 0.82 | TSHR (0.56) | CA2IDO1ESR1ESR2KMT2A | |
| SCHEMBL25375383 | 0.82 | APP (0.47) | IDO1KMT2AMEN1TSHRMAPK1 | |
| SCHEMBL1965032 | 0.82 | IDO1 (0.50) | IDO1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109461-A1 | BENZOTHIOPHENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国科学院上海药物研究所 | 2023-06-22 | — | — | WO | disclosed |
| CN-116265458-A | Benzothiophene derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-06-20 | — | — | CN | disclosed |
| US-20200057370-A1 | COMPOUND, RESIST COMPOSITION CONTAINING COMPOUND AND PATTERN FORMATION METHOD USING SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-02-20 | — | — | US | disclosed |
| WO-2001009072-A1 | PROCESS FOR THE PRODUCTION OF HYDROXY-SUBSTITUTED AROMATIC ALDEHYDES AND KETONES | PORT ELIZABETH TECHNIKON (ZA) | 2001-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200057370-A1 | COMPOUND, RESIST COMPOSITION CONTAINING COMPOUND AND PATTERN FORMATION METHOD USING SAME | CROCC, BICRA, TTC14 | CA2 4588/4885IDO1 4779/4885ESR1 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.