Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CTH | P32929 | 1/20 | 0.30 |
| ▸ | CBS | P35520 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375976 | 0.98 | THRB (0.39) | THRBCES2TSHRSMN1; SMN2 | |
| SCHEMBL19049755 | 0.98 | THRB (0.39) | THRBCES2TSHRSMN1; SMN2 | |
| SCHEMBL24840638 | 0.83 | THRB (0.36) | THRB | |
| SCHEMBL8669213 | 0.83 | THRB (0.32) | THRB | |
| SCHEMBL4391933 | 0.80 | — | — | |
| SCHEMBL5386683 | 0.79 | CES2 (0.30) | CES2 | |
| SCHEMBL24380474 | 0.79 | — | — | |
| SCHEMBL936619 | 0.79 | CES2 (0.35) | THRBCES2TSHRSMN1; SMN2CTH | |
| SCHEMBL8071570 | 0.78 | LMNA (0.33) | — | |
| SCHEMBL8854144 | 0.78 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882010-B1 | PHARMACEUTICAL AGENTS CONTAINING PERFLUOROALKYL-CONTAINING METAL COMPLEXES AND THE USE THEREOF IN TUMOUR THERAPY AND INTERVENTIONAL RADIOLOGY | SCHERING AG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-1999003509-A2 | PHARMACEUTICAL PRODUCTS CONTAINING TRIIODOAROMATS CONTAINING PERFLUOROALKYL GROUPS, AND THE USE THEREOF IN THE TREATMENT OF TUMOURS AND INTERVENTIONAL RADIOLOGY | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | disclosed |