SCHEMBL7939700

SCHEMBL7939700

CC(=O)OC(OC(C)=O)c1cccc(Oc2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.62
MEN1 O00255 1/20 0.56
CYP2D6 P10635 1/20 0.56
KMT2A Q03164 1/20 0.56
ALOX5 P09917 1/20 0.54
ALDH1A1 P00352 1/20 0.49
CYP3A4 P08684 1/20 0.49
AKR1C3 P42330 1/20 0.49
ACACB O00763 2/20 0.48
ACACA Q13085 2/20 0.48
NPY5R Q15761 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
GLI1 P08151 1/20 0.43
GLI2 P10070 1/20 0.43
HTR1D P28221 1/20 0.43
HTR1B P28222 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9862906 0.81 ALDH1A1 (0.59) PTGS1MEN1CYP2D6KMT2AALOX5
SCHEMBL10397026 0.81 ALDH1A1 (0.59) PTGS1MEN1CYP2D6KMT2AALOX5
SCHEMBL15151142 0.81 PTGS1 (0.58) PTGS1MEN1CYP2D6KMT2AALOX5
SCHEMBL9863162 0.81 ALDH1A1 (0.59) PTGS1MEN1CYP2D6KMT2AALOX5
SCHEMBL28186246 0.81 PTGS1 (0.62) PTGS1MEN1CYP2D6KMT2AALOX5
SCHEMBL486678 0.80 ALDH1A1 (0.63) CYP2D6KMT2AALDH1A1CYP3A4
SCHEMBL27601373 0.80 ALDH1A1 (0.51) PTGS1ALDH1A1CYP3A4
SCHEMBL10947140 0.80 ALDH1A1 (0.50) PTGS1MEN1CYP2D6KMT2AALDH1A1
SCHEMBL12608942 0.79 PTGS1 (0.84) PTGS1MEN1CYP2D6KMT2AALOX5
SCHEMBL14798131 0.79 ALDH1A1 (0.61) MEN1CYP2D6KMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6278019-B1 REACTING ALKYL GROUP SUBSTITUTED AROMATIC COMPOUND AND A CARBOXYLIC ACID AND/OR A CARBOXYLIC ANHYDRIDE IN PRESENCE OF OXYGEN CONTAINING GAS AND SOLID CATALYST SELECTED FROM COABLT, CERIUM AND MANGANESE SUPPORTED ON SOLID SUPPORT TORAY INDUSTRIES, INC. (JP) 2001-08-21 US disclosed
EP-0963974-A1 PROCESS FOR ACYLOXYLATING SIDE CHAINS OF ALKYL-SUBSTITUTED AROMATIC COMPOUNDS AND CATALYSTS USED THEREFOR TORAY INDUSTRIES, INC. (JP) 1999-12-15 EP disclosed
US-4014940-A Process for preparing m-phenoxybenzylalcohol and side-chain halogenated m-phenoxytoluene SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-03-29 US disclosed