SCHEMBL486678

SCHEMBL486678

CC(=O)OC(OC(C)=O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.63
CYP3A4 P08684 1/20 0.63
TSHR P16473 1/20 0.49
HSD17B10 Q99714 1/20 0.47
KMT2A Q03164 1/20 0.47
PABPC1 P11940 1/20 0.45
APOBEC3A P31941 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
CYP2D6 P10635 1/20 0.44
SRC P12931 1/20 0.44
HPGD P15428 1/20 0.44
LMNA P02545 2/20 0.43
MAPK1 P28482 2/20 0.43
HCAR2 Q8TDS4 1/20 0.43
GLS O94925 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14798131 0.98 ALDH1A1 (0.61) ALDH1A1CYP3A4TSHRHSD17B10KMT2A
SCHEMBL27679472 0.90 ALDH1A1 (0.54) ALDH1A1CYP3A4TSHRHSD17B10KMT2A
SCHEMBL6372424 0.90 ALDH1A1 (0.54) ALDH1A1CYP3A4TSHRHSD17B10KMT2A
SCHEMBL26284298 0.90 ALDH1A1 (0.54) ALDH1A1CYP3A4TSHRHSD17B10KMT2A
SCHEMBL1030015 0.90 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRHSD17B10KMT2A
SCHEMBL17863579 0.88 ALDH1A1 (0.48) ALDH1A1CYP3A4TSHRHSD17B10PABPC1
SCHEMBL4198693 0.88 PTGS2 (0.53) ALDH1A1CYP3A4
SCHEMBL24741372 0.87 ALDH1A1 (0.51) ALDH1A1CYP3A4TSHRHSD17B10KMT2A
SCHEMBL10947140 0.86 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRHSD17B10KMT2A
SCHEMBL19961191 0.86 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3993699-A IN AROMATIC SOLVENT HODOGAYA CHEMICAL CO., LTD. (JA) 1976-11-23 US claimed
JP-58146565-A None JP disclosed
JP-60243075-A None JP disclosed
JP-1045339-A None JP disclosed
EP-3745105-B1 TEMPERATURE DETECTION LABEL AND ARTICLE MANAGEMENT DEVICE USING SAME HITACHI LTD (JP) 2025-08-27 EP disclosed
US-20240400247-A1 TEMPERATURE INDICATOR MANUFACTURING SYSTEM AND TEMPERATURE INDICATOR MANUFACTURING METHOD HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) 2024-12-05 US disclosed
US-20240376065-A1 THIONOLACTONES, PROCESSES OF SYNTHESIS, USES AS COMONOMERS AND FOR POLYMER FUNCTIONALIZATION AND DEGRADATION SPECIALTY OPERATIONS FRANCE (FR) 2024-11-14 US disclosed
EP-4431889-A1 TEMPERATURE INDICATOR MANUFACTURING SYSTEM AND TEMPERATURE INDICATOR MANUFACTURING METHOD Hitachi Industrial Equipment Systems Co., Ltd. (JP) 2024-09-18 EP disclosed
US-12085452-B2 Temperature detection ink, temperature detection ink initialization method, temperature indicator, and article management system HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) 2024-09-10 US disclosed
EP-3614113-B1 TEMPERATURE DETECTING MATERIAL AND PRODUCT CONTROL METHOD HITACHI INDUSTRY EQUIPMENT SYSTEMS CO LTD (JP) 2024-07-17 EP disclosed
US-4535183-A PALLIATION OF SICKLE CELL ANEMIA, RESPIRATORY DISORDERS, HYPOXIA, RADIOSENSITIZATION OF TUMORS BURROUGHS WELLCOME CO. (US) 1985-08-13 US disclosed
US-4507510-A Process for producing xylyleneglycol MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-03-26 US disclosed
US-4410537-A 3-HYDROXY-2-FORMYLPHENOXYPENTANOIC ACID DERIVATIVES BURROUGHTS WELLCOME CO. (US) 1983-10-18 US disclosed
JP-S58146565-A 1,4-DIHYDROPYRIDINE DERIVATIVE MARUKO SEIYAKU KK 1983-09-01 JP disclosed
EP-0022229-B1 SUBSTITUTED PHENOL ETHERS, THEIR PREPARATION, INTERMEDIATES THEREFOR, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE PREPARATION THEREOF THE WELLCOME FOUNDATION LIMITED (GB) 1982-12-08 EP disclosed
EP-0054924-A2 Pharmaceutical compounds, their preparation and use THE WELLCOME FOUNDATION LIMITED (GB) 1982-06-30 EP disclosed
US-4250344-A Cracking process for styrene CHEM SYSTEMS INC. (US) 1981-02-10 US disclosed
EP-0022229-A1 Substituted phenol ethers, their preparation, intermediates therefor, pharmaceutical compositions containing them and the preparation thereof THE WELLCOME FOUNDATION LIMITED (GB) 1981-01-14 EP disclosed
US-3993699-A IN AROMATIC SOLVENT HODOGAYA CHEMICAL CO., LTD. (JA) 1976-11-23 US disclosed
US-3993699-A IN AROMATIC SOLVENT HODOGAYA CHEMICAL CO., LTD. (JA) 1976-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376065-A1 THIONOLACTONES, PROCESSES OF SYNTHESIS, USES AS COMONOMERS AND FOR POLYMER FUNCTIONALIZATION AND DEGRADATION TMT1A, TST, FDPS ALDH1A1 1238/4885CYP3A4 52/4885TSHR 2344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.