Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939828 | 0.84 | CTSL (0.57) | CTSLCTSSCTSKACEPTPN1 | |
| SCHEMBL7942088 | 0.81 | NPSR1 (0.47) | CTSLCTSSCTSKACECTSB | |
| SCHEMBL7942661 | 0.80 | PSMB5 (0.45) | ACE | |
| SCHEMBL8056323 | 0.80 | CTSL (0.58) | CTSLCTSSCTSKACEPTPN1 | |
| SCHEMBL25004063 | 0.80 | CTSL (0.62) | CTSLCTSSCTSKACEPTPN1 | |
| SCHEMBL111236 | 0.79 | ACE (0.76) | CTSLCTSSCTSKACEPTPN1 | |
| SCHEMBL528464 | 0.79 | ACE (0.76) | CTSLCTSSCTSKACEPTPN1 | |
| SCHEMBL111235 | 0.79 | ACE (0.76) | CTSLCTSSCTSKACEPTPN1 | |
| SCHEMBL28419446 | 0.77 | ACE (0.74) | CTSLCTSSCTSKACEPTPN1 | |
| Hydrochloric Acid SCHEMBL10622640 | 0.77 | ACE (0.74) | CTSLCTSSCTSKACEPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242448-B1 | Trisubstituted-oxazole derivatives as serotonin ligands | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | disclosed |
| EP-1053235-A1 | OXAZOLE DERIVATIVES AS SEROTONIN-1A RECEPTOR AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-22 | — | — | EP | disclosed |
| US-6057340-A | Oxazole derivatives as serotonin-1A receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |
| WO-1999038864-A1 | OXAZOLE DERIVATIVES AS SEROTONIN-1A RECEPTOR AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-08-05 | — | — | WO | disclosed |