Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942679 | 0.83 | PSMB5 (0.48) | PSMB5MEP1BANPEPSIGMAR1ATM | |
| SCHEMBL7939823 | 0.80 | CTSL (0.53) | ACE | |
| SCHEMBL24288429 | 0.78 | SIGMAR1 (0.56) | PSMB5MEP1BANPEPSIGMAR1ATM | |
| SCHEMBL7942088 | 0.78 | NPSR1 (0.47) | ATMACEALDH1A1MME | |
| SCHEMBL11581853 | 0.77 | MME (0.56) | PSMB5MEP1BANPEPSIGMAR1ALDH1A1 | |
| SCHEMBL73955 | 0.77 | MME (0.56) | PSMB5MEP1BANPEPSIGMAR1ALDH1A1 | |
| SCHEMBL497336 | 0.77 | MME (0.56) | PSMB5MEP1BANPEPSIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7362927 | 0.76 | MME (0.54) | PSMB5MEP1BANPEPSIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1027766 | 0.76 | MME (0.54) | PSMB5MEP1BANPEPSIGMAR1ALDH1A1 | |
| SCHEMBL1436736 | 0.75 | SLC7A5 (0.58) | ANPEPEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242448-B1 | Trisubstituted-oxazole derivatives as serotonin ligands | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | disclosed |