Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.39 |
| ▸ | ALDH1B1 | P30837 | 2/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6276074 | 0.93 | HMGCR (0.40) | HSD17B3ALDH1A1TSHRALDH1A2ALDH2 | |
| SCHEMBL167880 | 0.87 | HSD17B3 (0.36) | HSD17B3ALDH1A1TSHRHTTMAPT | |
| SCHEMBL9581030 | 0.74 | ALOX5 (0.46) | ALDH1A1TSHRHTTMAPTKDM4E | |
| SCHEMBL29368171 | 0.73 | ALDH1A1 (0.35) | HSD17B3ALDH1A1TSHRALDH1A2ALDH2 | |
| SCHEMBL156024 | 0.73 | ALDH1A1 (0.35) | HSD17B3ALDH1A1TSHRALDH1A2ALDH2 | |
| SCHEMBL22250960 | 0.71 | MCL1 (0.44) | ALDH1A1TSHRMAPTKDM4EHPGD | |
| SCHEMBL11792898 | 0.71 | GRIN2D (0.40) | HSD17B3ALDH1A1TSHRALDH1A2ALDH2 | |
| SCHEMBL22011795 | 0.70 | ALDH1A1 (0.38) | HSD17B3ALDH1A1TSHRALDH1A2ALDH2 | |
| SCHEMBL157308 | 0.68 | ESR1 (0.37) | HSD17B3ALDH1A1TSHRALDH1A2ALDH2 | |
| SCHEMBL8470589 | 0.68 | HSD17B3 (0.38) | HSD17B3ALDH1A1TSHRALDH1A2ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942947-B1 | FLAME-RESISTANT THERMOPLASTIC MOULDING COMPOUNDS BASED ON POLYARYLENE ETHERS | BASF AG (DE) | 2001-04-04 | — | — | EP | disclosed |