SCHEMBL157308

SCHEMBL157308

CCCc1cc2cc(CCC)c1o2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
ALDH1A1 P00352 6/20 0.34
KDM4E B2RXH2 3/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
TSHR P16473 3/20 0.33
HCAR2 Q8TDS4 2/20 0.33
HSD17B3 P37058 1/20 0.33
HMGCR P04035 1/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 1/20 0.33
ALDH1A2 O94788 1/20 0.33
ALDH2 P05091 1/20 0.33
ALDH1B1 P30837 1/20 0.33
ALDH1A3 P47895 1/20 0.33
CA12 O43570 1/20 0.33
FFAR3 O14843 1/20 0.32
POLB P06746 1/20 0.31
GPR84 Q9NQS5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368171 0.93 ALDH1A1 (0.35) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL156024 0.93 ALDH1A1 (0.35) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL156616 0.87 ALDH1A1 (0.37) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL29390534 0.87 ALDH1A1 (0.37) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL7606700 0.86 CTRC (0.40) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL29162700 0.85 ESR1 (0.33) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL29121538 0.85 ALOX5 (0.37) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL25415956 0.84 ALOX5 (0.40) ESR1ESR2TSHRHCAR2MAPT
SCHEMBL878089 0.82 ALOX5 (0.43) TSHRHCAR2MAPTHTTCYP3A4
SCHEMBL25417724 0.82 ALOX5 (0.43) TSHRHCAR2MAPTHTTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2048 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320359-A1 COMPOUNDING COMPOSITION APPLIED TO THE AIR CUTOFF VALVE FOR FUEL CELL VEHICLE HYUNDAI MOTOR CO LTD (KR) 2025-10-16 US claimed
CN-114395241-B Halogen-free high-gloss flame-retardant polystyrene material and preparation method and application thereof 金发科技股份有限公司 2025-03-25 CN claimed
CN-119613942-A Resin composition, resin adhesive film and application thereof 广东生益科技股份有限公司 2025-03-14 CN claimed
CN-113897047-B Thermoplastic molding composition and molded article 埃姆斯化学股份公司 2025-01-03 CN claimed
CN-119019805-A Resin composition, prepreg and metal foil-clad laminate 广东生益科技股份有限公司 2024-11-26 CN claimed
CN-116410563-B Resin composition, prepreg and metal foil-clad laminate 广东生益科技股份有限公司 2024-08-30 CN claimed
CN-114729180-B Polyphenylene ether resin composition and molded article 旭化成株式会社 2024-08-27 CN claimed
CN-114040942-B Styrene resin composition 出光兴产株式会社 2024-07-26 CN claimed
WO-2024133438-A1 THERMOPLASTIC ELASTOMER COMPOSITION, PROCESS FOR ITS PRODUCTION, AND WEAR RESISTANT PARTS OBTAINED THEREBY INDUSTRIE ILPEA S.P.A. (IT) 2024-06-27 WO claimed
WO-2024132101-A1 THERMOPLASTIC ELASTOMER COMPOSITION, PROCESS FOR ITS PRODUCTION, AND WEAR RESISTANT PARTS OBTAINED THEREBY INDUSTRIE ILPEA S.P.A. (IT) 2024-06-27 WO claimed
EP-0199510-A2 Polyphenylene ether resin composition Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-10-29 EP claimed
EP-0052854-B1 POLYPHENYLENE OXIDE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-07-02 EP claimed
US-4483958-A BLEND OF AROMATIC POLYETHER, STYRENE POLYMER, FILLER, AND ELASTOMER ASAHI-DOW LIMITED (JP) 1984-11-20 US claimed
US-4456736-A PRETREATING SOLID PHASE POLYPHENYLENE ETHER WITH FREE RADICAL CATALYST, THEN VAPOR PHASE GRAFT POLYMERIZATION WITH UNSATURATED COMPOUND KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-06-26 US claimed
EP-0017939-B1 METHOD FOR PRODUCING MODIFIED POLYPHENYLENE OXIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-20 EP claimed
US-4338410-A IN THE PRESENCE OF IXIME OR NITROSO COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-07-06 US claimed
EP-0052854-A1 Polyphenylene oxide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-02 EP claimed
US-4283511-A GRAFT POLYMERIZATION WITH A STYRENE MONOMER AND A POLAR VINYL MONOMOER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-08-11 US claimed
EP-0017751-A1 Process for the production of graft copolymers of polyphenylene oxides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-10-29 EP claimed
EP-0017939-A1 Method for producing modified polyphenylene oxides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-10-29 EP claimed