Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937309 | 0.88 | HTT (0.64) | HTTPOLBTSHRALDH1A1LMNA | |
| SCHEMBL2366286 | 0.88 | HTT (0.47) | HTTPOLBTSHRALDH1A1LMNA | |
| SCHEMBL7934118 | 0.81 | ALDH1A1 (0.46) | HTTPOLBTSHRALDH1A1LMNA | |
| SCHEMBL14686936 | 0.78 | MEN1 (0.58) | HTTPOLBTSHRALDH1A1LMNA | |
| SCHEMBL14687557 | 0.77 | ALDH1A1 (0.48) | HTTPOLBTSHRALDH1A1LMNA | |
| SCHEMBL2365944 | 0.77 | ALDH1A1 (0.46) | HTTPOLBTSHRALDH1A1LMNA | |
| SCHEMBL2366976 | 0.76 | HTT (0.64) | HTTPOLBTSHRALDH1A1LMNA | |
| SCHEMBL19446927 | 0.75 | HTT (0.67) | HTTPOLBTSHRALDH1A1LMNA | |
| SCHEMBL7940439 | 0.74 | KDM4E (0.41) | ALDH1A1L3MBTL1RAB9AMEN1KMT2A | |
| SCHEMBL14687068 | 0.73 | LMNA (0.47) | HTTTSHRALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050461-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | 田辺三菱製薬株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |