Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366178 | 0.89 | KDM4E (0.41) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7934118 | 0.85 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14687163 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27829805 | 0.80 | OPRK1 (0.41) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2366042 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27892670 | 0.79 | OPRK1 (0.40) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14686750 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2366602 | 0.77 | SLC6A7 (0.42) | KDM4EALDH1A1MEN1KMT2ASLC6A7 | |
| SCHEMBL19446933 | 0.77 | LMNA (0.46) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14687002 | 0.77 | TRPC6 (0.42) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050461-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | 田辺三菱製薬株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |