SCHEMBL7939877

SCHEMBL7939877

CCCCCCCCCC(C)C=CC(=O)CC(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.41
ACE2 Q9BYF1 1/20 0.40
CA1 P00915 2/20 0.39
FFAR1 O14842 1/20 0.39
ZDHHC7 Q9NXF8 1/20 0.39
MAPT P10636 2/20 0.38
LCK P06239 1/20 0.38
PPARD Q03181 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
ADH1B P00325 1/20 0.37
ADH1C P00326 1/20 0.37
ADH1A P07327 1/20 0.37
ADH4 P08319 1/20 0.37
ADH7 P40394 1/20 0.37
CA2 P00918 1/20 0.37
FFAR4 Q5NUL3 1/20 0.36
TRPA1 O75762 1/20 0.36
DDAH1 O94760 1/20 0.36
GAPDH P04406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7939874 1.00 GPR84 (0.41) GPR84ACE2CA1FFAR1ZDHHC7
SCHEMBL7940960 0.81 CA1 (0.38) GPR84ACE2CA1FFAR1MAPT
SCHEMBL7940963 0.81 CA1 (0.38) GPR84ACE2CA1FFAR1MAPT
SCHEMBL29177079 0.80 ACHE (0.47) GPR84ACE2CA1FFAR1MAPT
SCHEMBL8948019 0.80 ACE2 (0.43) GPR84ACE2CA1FFAR1ZDHHC7
SCHEMBL8948016 0.80 ACE2 (0.43) GPR84ACE2CA1FFAR1ZDHHC7
SCHEMBL11598836 0.79 MAPT (0.42) GPR84ACE2CA1FFAR1ZDHHC7
SCHEMBL8948043 0.78 CA1 (0.44) GPR84ACE2CA1FFAR1ZDHHC7
SCHEMBL13611716 0.78 ACHE (0.41) ACE2CA1CA2TRPA1
SCHEMBL30527786 0.78 ACHE (0.49) GPR84ACE2CA1FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6288288-B1 ALDOL CONDENSATION OF ALKYL METHYL KETONE, HYDROGENATION OF ALPHA, BETA UNSATURATED KETONES TO ALCOHOLS IN THE PRESENCE OF ALKALI METAL HYDROXIDE CELANESE GMBH (DE) 2001-09-11 US disclosed