Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 2/20 | 0.33 |
| ▸ | GLP1R | P43220 | 9/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7940603 | 0.85 | CD274 (0.35) | KDM5AKDM4CKDM5BGLP1RHRH2 | |
| SCHEMBL7940020 | 0.83 | ALDH1A1 (0.38) | — | |
| SCHEMBL14952909 | 0.81 | GUCY1B2 (0.44) | — | |
| SCHEMBL7939410 | 0.79 | ALDH1A1 (0.38) | HRH2HRH1 | |
| SCHEMBL7944082 | 0.75 | NEK2 (0.36) | KDM5AKDM4CKDM5BPDCD1CD274 | |
| SCHEMBL3229063 | 0.74 | GUCY1B2 (0.45) | — | |
| SCHEMBL3239175 | 0.74 | GUCY1B2 (0.40) | HRH2HRH1 | |
| SCHEMBL4005210 | 0.74 | GLP1R (0.40) | GLP1RPDE10A | |
| SCHEMBL3234836 | 0.71 | L3MBTL1 (0.44) | — | |
| SCHEMBL3233312 | 0.70 | GUCY1B2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015652-A2 | THIAZOLE COMPOUNDS AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-11 | — | — | WO | disclosed |