Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | F13A1 | P00488 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517048 | 0.72 | FABP4 (0.61) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL7511654 | 0.71 | FABP4 (0.59) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL7511658 | 0.70 | FABP4 (0.61) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL4265168 | 0.69 | FABP4 (0.34) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL4258883 | 0.69 | FABP4 (0.59) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL7518601 | 0.68 | NPSR1 (0.38) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL7517054 | 0.68 | F2 (0.41) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL7522685 | 0.67 | F2 (0.40) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL7516866 | 0.67 | F2 (0.40) | FABP4CA1CA2MMP1MMP2 | |
| SCHEMBL4746886 | 0.65 | NR3C1 (0.36) | FABP4CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235794-B1 | ANTICANCER AGENT | UNIVERSITY OF FLORIDA | 2001-05-22 | — | — | US | disclosed |