Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | F13A1 | P00488 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | THPO | P40225 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249429 | 0.77 | ALDH1A1 (0.35) | CA2CA1PAOXCA12ALOX15 | |
| SCHEMBL5605132 | 0.75 | ALDH1A1 (0.35) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL7511658 | 0.72 | FABP4 (0.61) | FABP4CA2CA1MMP1MMP2 | |
| SCHEMBL4258883 | 0.71 | FABP4 (0.59) | FABP4CA2CA1MMP1MMP2 | |
| SCHEMBL7517048 | 0.70 | FABP4 (0.61) | FABP4CA2CA1MMP1MMP2 | |
| SCHEMBL7940206 | 0.69 | FABP4 (0.34) | FABP4CA2CA1MMP1MMP2 | |
| Norspermidine SCHEMBL28331693 | 0.69 | CA12 (0.57) | CA2CA1PAOXCA12F13A1 | |
| SCHEMBL7511654 | 0.69 | FABP4 (0.59) | FABP4CA2CA1MMP1MMP2 | |
| SCHEMBL7937672 | 0.65 | FABP4 (0.36) | FABP4CA2CA1MMP1MMP2 | |
| SCHEMBL7517054 | 0.65 | F2 (0.41) | FABP4CA2CA1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676798-B2 | Cationic oligonucleotides, automated methods for preparing same and their uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-06-13 | — | — | US | disclosed |
| US-20160280728-A1 | CATIONIC OLIGONUCLEOTIDES, AUTOMATED METHODS FOR PREPARING SAME AND THEIR USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-09-29 | — | — | US | disclosed |
| US-9090648-B2 | Cationic oligonucleotides, automated methods for preparing same and their uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-07-28 | — | — | US | disclosed |
| EP-1973927-B1 | CATIONIC OLIGONUCLEOTIDES, AUTOMATED METHODS FOR PREPARING SAME AND THEIR USES | CENTRE NAT RECH SCIENT (FR) | 2013-08-14 | — | — | EP | disclosed |
| US-20090069262-A1 | Cationic Oligonucleotides, Automated Methods for Preparing Same and Their Uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-03-12 | — | — | US | disclosed |
| EP-1973927-A2 | CATIONIC OLIGONUCLEOTIDES, AUTOMATED METHODS FOR PREPARING SAME AND THEIR USES | Centre National De La Recherche Scientifique-CNRS (FR) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007069092-A2 | CATIONIC OLIGONUCLEOTIDES, AUTOMATED METHODS FOR PREPARING SAME AND THEIR USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280728-A1 | CATIONIC OLIGONUCLEOTIDES, AUTOMATED METHODS FOR PREPARING SAME AND THEIR USES | HNRNPH3, SRM, SNRPB2 | FABP4 3620/4885CA2 4159/4885CA1 2637/4885 |
| US-20090069262-A1 | Cationic Oligonucleotides, Automated Methods for Preparing Same and Their Uses | HNRNPH3, RNASEH1, SRM | FABP4 3520/4885CA2 4271/4885CA1 2885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.