Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.30 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698147 | 0.82 | ACE (0.39) | ACEALDH1A1 | |
| SCHEMBL5698066 | 0.75 | ALDH1A1 (0.43) | ALDH1A1SPHK1SPHK2MAPT | |
| SCHEMBL11228772 | 0.65 | SLC6A2 (0.34) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL28911976 | 0.59 | SPHK1 (0.53) | ACENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7200882 | 0.58 | HRH3 (0.48) | SMN1; SMN2ALDH1A1HPGDHSD17B10SPHK1 | |
| SCHEMBL7454243 | 0.57 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11616221 | 0.56 | ESR1 (0.46) | ALDH1A1HSD17B10SPHK1SPHK2 | |
| SCHEMBL18113297 | 0.56 | RARB (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL24295037 | 0.55 | ALDH1A1 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL26770766 | 0.55 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10NAAAASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242476-B1 | Leukotriene A4 hydrolase inhibitors | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | claimed |
| US-6242476-B1 | Leukotriene A4 hydrolase inhibitors | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |