Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235013 | 0.84 | LMNA (0.34) | SLC6A2SLC6A3LMNASLC6A4SMN1; SMN2 | |
| SCHEMBL11243304 | 0.77 | LMNA (0.37) | SLC6A2SLC6A3LMNASLC6A4SMN1; SMN2 | |
| SCHEMBL11228481 | 0.76 | MAPT (0.32) | — | |
| SCHEMBL4452654 | 0.71 | — | — | |
| SCHEMBL11234497 | 0.71 | SLC6A2 (0.33) | SLC6A2SLC6A3LMNASLC6A4SMN1; SMN2 | |
| SCHEMBL5698108 | 0.70 | ACE (0.39) | POLBALDH1A1 | |
| SCHEMBL7342204 | 0.70 | — | — | |
| SCHEMBL5698105 | 0.70 | RXRA (0.33) | LMNAALDH1A1 | |
| SCHEMBL5698075 | 0.69 | ACE (0.39) | — | |
| SCHEMBL5698079 | 0.69 | ACE (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316905-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |