SCHEMBL7940388

SCHEMBL7940388

C#Cc1ccc2ccccc2c1O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 1/20 0.54
CYP1A2 P05177 2/20 0.46
LDHA P00338 1/20 0.46
HSD17B10 Q99714 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP2A6 P11509 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 1/20 0.42
CYP2C19 P33261 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20699497 0.82 ALDH1A1 (0.39) PTPN22CYP1A2HSD17B10ALDH1A1HIF1A
SCHEMBL3076721 0.79 PTPN22 (0.54) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL2231383 0.79 PTPN22 (0.54) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL31676618 0.77 CYP2A6 (0.46) PTPN22CYP1A2HSD17B10ALDH1A1CYP2A6
SCHEMBL5431973 0.77 CYP2A6 (0.46) PTPN22CYP1A2HSD17B10ALDH1A1CYP2A6
SCHEMBL28497043 0.76 PTPN22 (0.50) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL689190 0.75 ALDH1A1 (0.44) CYP1A2HSD17B10ALDH1A1CYP2A6TSHR
SCHEMBL20699536 0.75 ALDH1A1 (0.39) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL15414319 0.75 HSD17B10 (0.44) PTPN22CYP1A2HSD17B10ALDH1A1CYP2A6
SCHEMBL12531094 0.74 ALDH1A1 (0.35) HSD17B10ALDH1A1TDP1HPGDHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11360387-B2 Silicon-containing underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2022-06-14 US disclosed
US-20190041751-A1 SILICON-CONTAINING UNDERLAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-02-07 US disclosed
EP-0834499-B1 Process for the preparation of aromatic vinyl compounds DAINIPPON INK & CHEMICALS (JP) 2001-07-25 EP disclosed
EP-0834499-A1 Process for the preparation of aromatic vinyl compounds DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-04-08 EP disclosed
US-4221895-A POLYESTER, POLYSULFONATE, OR POLYSULFINATE THE DOW CHEMICAL COMPANY (US) 1980-09-09 US disclosed