Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929013 | 0.86 | MDM2 (0.52) | KMT2AALDH1A1GSK3BSLC6A3SLC6A2 | |
| SCHEMBL7634475 | 0.84 | KMT2A (0.49) | KMT2AALDH1A1SMN1; SMN2GSK3BSLC6A3 | |
| SCHEMBL9353004 | 0.82 | SLC6A3 (0.54) | KMT2AALDH1A1SMN1; SMN2GSK3BSLC6A3 | |
| SCHEMBL9356303 | 0.79 | SLC6A3 (0.48) | KMT2AALDH1A1SMN1; SMN2GSK3BSLC6A3 | |
| SCHEMBL2289091 | 0.78 | ALDH1A1 (0.50) | KMT2AALDH1A1SMN1; SMN2GSK3BSLC6A3 | |
| SCHEMBL9352239 | 0.78 | L3MBTL1 (0.47) | KMT2AALDH1A1SMN1; SMN2GSK3BSLC6A3 | |
| SCHEMBL9352257 | 0.77 | L3MBTL1 (0.50) | KMT2AALDH1A1SMN1; SMN2GSK3BSLC6A3 | |
| SCHEMBL9352280 | 0.77 | L3MBTL1 (0.50) | KMT2AALDH1A1SMN1; SMN2GSK3BSLC6A3 | |
| SCHEMBL9352667 | 0.77 | L3MBTL1 (0.50) | KMT2AALDH1A1SMN1; SMN2GSK3BSLC6A3 | |
| SCHEMBL9352846 | 0.77 | L3MBTL1 (0.50) | KMT2AALDH1A1SMN1; SMN2GSK3BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010020112-A1 | Process for preparing (hetero) aromatic substituted benzene derivatives | TOYA TETSUYA (JP) | 2001-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020112-A1 | Process for preparing (hetero) aromatic substituted benzene derivatives | AHR, CYP3A4, CYP4B1 | KMT2A 2559/4885ALDH1A1 1596/4885SMN1; SMN2 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.